
MOTS-c
Sale20 mg · 40 mg
Mitochondria-targeting tetrapeptide
10 mg

SS-31 is a synthetic tetrapeptide in the Szeto-Schiller peptide family. It interacts with cardiolipin, a lipid concentrated in the inner mitochondrial membrane, where cells carry out much of their energy production.
Experiments using isolated mitochondria and model membranes have examined how SS-31 affects the interaction between cardiolipin and cytochrome c, a protein involved in electron transport. This work focuses on mitochondrial respiration, ATP synthesis and membrane function. The peptide's alternating aromatic and positively charged residues are part of its distinctive structure.
| Material identity | SS-31 (Szeto-Schiller tetrapeptide) |
|---|---|
| Amount per vial | 10 mg |
| Available amounts per vial | 10 mg or 50 mg |
| Compound type | Synthetic tetrapeptide |
| Form | Lyophilized material |
| Peptide family | Szeto-Schiller |
|---|---|
| Peptide length | 4 amino acids |
| Sequence | D-Arg-Dmt-Lys-Phe-NH2 |
| Sequence notation | Dmt means 2,6-dimethyltyrosine; NH2 indicates C-terminal amidation |
SS-31 interaction with cardiolipin and mitochondrial electron transport.
For research use only.